BACKGROUND In the early 1950’s, a young Belgian medical doctor with a passion for pharmacology, Paul Janssen, combined his altruistic…
To score…or not to score…? Suicide risk in the ED
On a dark and brooding autumn night, you once again find yourself healing the injured, curing the sick, and reassuring…
The tPA vs PCI for STEMI Slapdown – The STREAM trial 1-year mortality follow-up
Early last year the folks at Boehringer-Ingelheim (who manufacture and sell tenecteplase) sponsored the STREAM trial, which I have previously discussed…
Thrombolysis vs delayed PCI for STEMI – the STREAM trial (+ 1 case study)
Published in the NEJM last April was a study titled “Fibrinolysis or Primary PCI in ST-Elevation Myocardial Infarction”… or “the…
The Yellow Brick Road to Metabolic Armageddon
BACKGROUND 2,4-dinitrophenol, or simply DNP to its friends, is a small, simple, innocent-looking aromatic compound which has been intentionally synthesised…
Sick of Ondansetron? Sniff some alcohol instead…
Tim Minchin is famous for a number of reasons, chiefly for being a brilliant Aussie musician, lyricist and comedian.…
Wheezing in the City of Lights
The PARIS Trial – High-Flow Oxygen in Bronchiolitis The timing of the publication of the PARIS (Paediatric Acute Respiratory Intervention…
Weapons of Choice – 2nd Antiplatelet Agents in ACS
INTRODUCTION While it is well-established that dual antiplatelet (AP) therapy is more effective than aspirin alone in patients presenting with…